Question

3. How to obtain (in one or more steps): a. Aniline from benzoic acid b. N-methylaniline from nitrobenzene 4. Sort the following amines according to increasing alkalinity in water solution: amonia, triethylamine diethylamine, aniline, methylamine, diphenylamine, 4-methoxyaniline 5. Describe two methods for obtaining secondary and two methods for obtaining tertiary amines.

Answer 1

3. How to obtain Cin one or more steps) a Aniline from benzoic acid CONH2 Cool soc . cool N Benzoic acid Benzoyl chloride Benzamide Brz/NaOH (Hoffmann vec") AH2 Aniline b] N-methylaniline from oitrobenzene : N02 NH2 HNCH3 SnT conc. HCE CH3 I +AZ nitrobenzene Aniline N-methylanilised 4. Sort the following amines according to increasing alkalinity in water solution. | Alkalinity is the capacity of water to resist changes in pH that would make the water more acidic Alkalinity is a measure of a capacity of water to neutralize acids.. Ammonial triethylamine (diethylamine (methylamine { aniline { dipherylamine { G mcthyacilis

5 Describe the methods for obtaining secondary and two - for tertiary amine. Porep & C2H5NH2 + CH3-C-cl Pyridine C2H5-NH-C-CH3 + HCl ethylamine. Noethyl acetamide 48H5NH2 KOH (Wolf kishner C2H5– NH-CH2-CH3 zoamine (N-ethyl ethanamine) u & C2H5-NH2 + chaha hch3 pyridine Cahs-NH-C-CH3 ethylamine Acetic anhydride. N-ethylacetamide + CH3COOH NH2-NH2 -ROH C2H - NH-CH2-CH3 20 amine N-ethyl ethanamine- The obtaining of a Secondary amine p The action of acetyl chloride on a primary amine to get N-ethyl acetamide which on Reduction by using hydrazine to give secondary amine & The action of acetic anhydride to get a amide on reduction on a to primary amine give Secondary Lamine

51. Descoibe two methods for obtaining secondary and two method for obtaining tertiary amines. Preparation of 3° amines. 1 (C2H5), NH + CH3 ---Pythang (CHS), NFC-CH3 + HCl Acid chloride A Nethyl ethanomine (N,N-diethyl acetamide) NH2-NH2 KOH (C2H5) N-6245 30 amine N,N-diethyl ethananine 2 (CGHS)₂NH + CH3-C-0-¢-CH3 pyndine (Cats), NH (CH3 Ha-NH2 KOHA (6245),N- c245 -3° amine. N,N-diethyl ethanamine
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