Question

Select the steps that will drive you through the synthesis (more than one).

میمہ multiple steps کل . Z-I MgBr SOC12 1. LiAIHA CH3OH لما .1 2. H20 هر هر 2 NH2 هHo EtaN NaBH9CN, pH6 EtzN

I thought about a hydrolysis first to get to an amide. Then we would also need D in order to add the right alkyl part, but cannot figure the whole sequence.

Answer 1

In the first step, the cyanide on complete hydrolysis produces carboxylic acid as the product which on reaction with SOCl2 produces acid chloride. The formed acid chloride on treatment with triethyl amine (base) and amine gives the amide as the product.

so som Hot EN Ha complete hydrolysis