Question

Write a stepwise mechanism for + H2O Oi houth Where is the Ois? In the Н,0 lactone 50% in each The chiral center in the lactone, relative to A is retained inverted scrambled There is another analogous product conditions. Draw the structure of C. that would also form from A under these If the system were allowed to come to equilibrium, what species would predominate A. B, or C?

Answer 1

HO HO 18 H6 018 will be in lactone only becowe acid ger protonated & makes carbonat carbon more electrophilic later oxygen 18 will attack on carbonyl carbon to leares water molecule which again neutralizes eactone to get lactone ®. The chiral centre will get retained in molecule of dactine. The structure of a It system, were allowed to come to equillibrium then more stable product will be product & & B predominanth product because it is to membered S. lactone.