Question

Devise the most efficient synthesis for the carbo acid below using a starting material and reagents from the table Give yo route by specifying the number of the starting material followed by the letters of the reagents you would use beginning with the step. The answer 4fh means treat t-butanol (4) with conc. HCl(f then treat the product with KoH in alcohol(h). OH Starting materials Br Br OH H3C OH OH Reagents e Aqueous H2SO4 at reflux a Mg dry ether b 1. CO2 2. acidic workup j Na2 Cro4 aqueous H2SO4 f Conc, HCI or HCI (gas) c NaCN /THF or DMF g PBr k 1. BH3 THF 2, H202 aq. NaoH h KOH alcohol d NaCN /dil. aqueous H2SO4 Previous The most efficient synthetic route is 4

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Answer #1

Any er..(c)→ @丁( Ceh tsMnoy cooH 5J อ从 der 1 1<ト1 no 8 Hsof

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