Draw the product for the multi-step synthesis shown below. You may draw the intermediate products for...
The use of Grignard reagents in multi-step synthesis is widely employed. For each of the reaction sequences below, draw the major organic product that would be present after each reaction of the sequence. No mechanisms, no explanations, just draw the products (in total, 14 reaction products A to N are required). You may have to consult your lecture material and/or the textbook to solve some of these problems The use of Grignard reagents in multi-step synthesis is widely employed. For...
Multi-step synthesis ci R R NH, OEt А OH B 1. Br2 / uv light 2. SOCI2 / THE 3. Mg/Et20 4. Meu/hexane S. CH3CH2MgCl 6. Ph MgBe 7. NaBHA 8. LAHA 9. BH3 /OX 10. POCl/pyridine/ THF 11.03/THE 12. PCC / CH2 13.H/H20 14. ELOH/H 15. t-butaxide 16. OH/H20 17. NHS 18.CO2 19. acetic anhydride 20.HNMez/THE In each box, type out the list of reagents in proper order that will carry out the synthesis of the final product (This...
9. P ropose a multi-step synthesis to accomplish the overall transformation shown below (make the molecule on the right starting with the molecule on the left). Show all necessary reagents and products for each forward step. [It is not necessary to show any mechanisms.] OH 10. Propose a multi-step synthesis to accomplish the overall transformation shown below (make the molecule on the right starting with the molecule on the left). Show all necessary reagents and products for each forward step....
2. Synthesis: Fill in the missing products in the synthesis process below. Stereochemistry should be shown if applicable. Br m-CPBA NaOEt DMSO H+ MeOH 1. Predicting Products/reagents: Draw the structure of the reagents or the major organic product(s) of each reaction in the boxes provided. Stereochemistry should be shown if applicable. 1) xs LAH, Et20 2) H20 CI HO CI OH CI pyridine
Chemistry 2320 Ch 18 Aldehydes and Ketones (100 pts) 3. Provide the most efficient synthesis possible by matching the reagents to the reaction. Write the letter (3) over or adjacent to the corresponding reaction arrow. As many as three steps represented by each letter may be needed. Assume intermediate products are isolated and purified or used in situ as appropriate. A. HOVOH B. HN(CH3)2, H' OH XCN C. Na2Cr2O, H2SO4 LOH Ph D. CH,MgBr, Eto E. HCN F. LiAIH, THE...
Consider the two‑step synthesis of cyclopentanecarboxylic acid from cyclopentanol. Identify the missing reagents and draw the intermediate formed. Draw the intermediate. reagent A Intermediate reagent E 2. CO2 3. H3o он Identify reagent A. PBr PCC NaH NaBH Identify reagent B. acetone Mg in ether ethyl acetate ethylene oxide
(10 points) Draw the correct product for the reaction below. For step 2, draw the reaction mechanism. Be sure to include important intermediate compounds, electron flow arrows, and formal charges for full credit. ОН 1. SOCl2, pyridine 2. CH3NH2 (10 points) Fill in the boxes with the missing starting material, intermediate products, reagents, and/or products. Then for each reaction draw the reaction mechanism with Correct electron flow arrows if appropriate or intermediates and correct formal charges. -OH -NH2 NH (10...
Specify the reagent you would use in each step of the following synthesis: step 1 step 2 CHCH3 Reagents Available a. LiAlH4 b. H2SO4 f. PBrz 9. pyridinium chlorochromate (PCC) h. Nah c. HCI K. CH3CH2MgBr I. CHgMgBr (phenylmagnesium bromide) m. (CH3)2CHMOBI n. Cro3 d. HB i. NaOH e. SOCI j. CH3 MgBr Write the letters of the reagents in the boxes below. Reagent for step 1 Reagent for step 2 A(C4H100) reacts with phosphorus tribromide to give B(C4H,Br). B...
20% Multi-Step Synthesis Sa) Show how you could perform the following synthesis. You may use any reagents that you need. 20% Multi-Step Synthesis Sa) Show how you could perform the following synthesis. You may use any reagents that you need.
A Br 31. Provide the final product that results upon completion of the multi-step synthesis shown: NaOme MeOH NaOME H30 PhP=CH2 I dil ? Оме HCI Br NaOme OH OH P+Ph Br A. Br C. D. B. CO2H