ketone products can be efficiently constructed by
sequential Friedal-Crafts acylations with phosgene.
a- draw an arrow pushing mechanism for the double acylation and
predict the final product
b-draw the major resonance contributor of the sigma complex formed
in the first acylation
I HOPE ITS HELPFUL TO YOU..IF YOU HAVE ANY DOUBTS PLS COMMENTS BELOW..I WILL BE THERE TO HELP YOU..ALL THE BEST...
I HOPE ITS HELPFUL TO YOU..PLS RATE THUMBS UP...ITS HELPS ME ALOT....
THANK YOU.....!!
ketone products can be efficiently constructed by sequential Friedal-Crafts acylations with phosgene. a- draw an arrow...
VI. Mechanism. (14) 1. Draw a stepwise electron pushing mechanism to predict the products in the following reduction. Make sure to show the correct locations of any deuterium (D) labels (4) 1. LA EXCESS) Co che le 2 0,09 2. Draw a complete stepwise electron pushing mechanism for the acylation of toluene below. Make sure to clearly indicate the role of the catalyst and how it is regenerated. Also clearly indicate why the methyl substituent directs the cyl group to...
сн, Нас 12-addition products (direct addition) CH2 CH3 Н,с Н-с CH CI HCI CH2 Cн Н.с 1,4-addition products (conjugate addition) Cн CH3 Нас Н.С CI Electrophilic addition to an alkene proceeds via Markovnikov regiochemistry due to the formation of the more stable carbocation intermediate. In the case of conjugated dienes, that is dienes that are separated by one sigma bond, the carbocation that is formed is stabilized additionally by resonance. Addition of the nucleophile to the carbocation intermediate can therefore...