1 (21 points) Predict the major product(s) for each transformation below. Indicate the stereochemistry where applicable....
predict the major product for each transformation
below,indicate the stereochemistry where appicable.assume all
reaction will take place
(28 points) Predict the major product(s) for each transformation below. Indicate the stereochemistry where applicable. Assume that all the reactions will take place. BE TEA, CH,Cl2 heat hv NaNH, DMF De Cl,H,O OH 1. Hg(OAc)2(aq). 2. NaBH(aq) CICCIA 1.03,CH,CI 2. S
predict the products of rach reaction below. indicate
regiochemistry and stereochemistry when relevant.
CH; HH CH212 c=Ć Zn(Cu), ether HzC CH3 1.03, CH C12 2.Zn, HOẶC tu 1. HOOAC), H20 2. NaBH4 CH3 KMnO4 H307 CH=CH2 12 н н 13. HIO4 HO 14. ОН
1. Give the major product of the following reactions, write N.R.
if no reaction happens. Indicate the stereochemistry if
necessary:
1. Give the major product of the following reactions, write N.R. if no reaction happens. Indicate the stereochemistry if necessary: CHCl3 KOC(CH3)3, (CH3)3COH 1. conc. HBr, heat 2. KOBU, HOBU ✓ 1. NaoMe, MeOH 2. BrCN 1. 1 eq. BH3, THE 2. H2O2, NaOH, H20 3. Hg(OAc)2, MeOH 4. NaBH4, NaOH, H20
4. Predict the products, Indicate stereochemistry when applicable а HBr H2S04 H20 1. Hg(OAC), H20 2. NaBH4 1.BH3 2. H2O2, NaOH> Br2 Cl2 H20
3. Predict the majoe product(s) for the following reactions. Show the stereochemistry of the product(s) when applicable. HCI (1) Hg(OAc)2 (2) NaBH4 (1) BH3 THF (2) H202. OH Br, Br2. H20 Pt (I) CH3CO3H (2) H,O+ (2) DMS HBr ROOR
1. Give the major product of the following reactions, write N.R.
if no reaction happens. Indicate the stereochemistry if
necessary:
1. conc. HCI 2. LDA, THE 3. O3, CH3OH 4. (CH3)2S N2 hv 1. Hg(OAC)2, THE 2. NaBH4, NaOH, H20 Y-OH (Hint: product has a bicyclic ring)
write a major product for each of the following reaction,
indicate appropriate stereochemistry
1. Br2, hv (a) 2. NaOCH3, Cн,Он, Д 1. x's NaNH2 3. KMnO4, H30 X, cold (c) .CI 2. Br Br 3. K, NH3(), CH3CH2OH 4. CHCI3 NaOH(aq) 1. H2SO4 Он (b) 2. CH3COOOH 3. Нао х
3. Predict the major product(s) for the following reactions. Show the stereochemistry of the product(s) when applicable. (a) (e) Br2, H20 H2 PL (1) Os04 (2) NaHSO4, H20 (1) 03 (2) DMS (1) CH2CO3H (2) H30*
(5 pts) 1. Predict the structure of the product of the following reaction. Show the stereochemistry, where applicable. 1. BH3, THE CH3CH2C= CH 2. H2O2; NaOH, H20 -CH2C= CCH2CH3 NH3 Excess HBT CH3CH2CH2C=C-CH3 1 Equiv. Br2 CH3CH2CH2C=C—CH3 CH3CH2CH2C=C—CH3- 1.03 2. Zn, H30*
In each reaction Predict the major organic product(s). Where
necessary show appropriate stereochemistry and regiochemistry. DO
NOT DRAW THE MECHANISM!
1) Br/FeBr 2) Separate p-isomer 3) CH3CH2B(OR)2/PdL2/NaOH 4) KMnO4/NaOH/A 5) H 0 1) Br2/FeBr3 2) Separate p-isomer 5) H30 3) CH3CH2B(OR)2 4) KMnO4/NaOH/A PdL2/NaOH C. C.