Q7.19: Identify the substitution product that is expected when 1-bromo-1-methylcyclohexane undergoes an Sn1 reaction in the...
(a) When cis-1-bromo-2-methylcyclohexane undergoes an E2 reaction, two products (cycloalkenes) are formed. What are these two cycloalkenes, and which would you expect to be the major product? Write conformational structures showing how each is formed. (b) When trans-1-bromo-2-methylcyclohexane reacts in an E2 reaction, only one cyclo- alkene is formed. What is this product? Write conformational structures showing why it is the only product.
7. Predict the SN2 product of this reaction: NaOH CHOH 8. 1-bromo-2-methylcyclohexane reacts via an SN1 mechanism to produce 2 products. Draw the carbocation intermediate that led to each individual product. Qarakia
on (R)-1-bromo-2-methylbutane undergoes substitution when reacted with sodium iodide (Nal) in acetone. Choose the major product obtained from this reaction. A (R)-1-iodo-2-methylbutane B (S)-1-iodo-2-methylbutane C racemic 1-iodo-2-methylbuta D (R)-1-bromo-2-iodobutane E (S)-1-bromo-2-iodobutane F (S)-1-sodium-2-methylbutane Enter Your Answer: OA OB OC OD OE OF B Incorrect
Question 6 - 10 pts. Homework • Unanswered When (cis)-1-bromo-2-methylcyclohexane is treated with methanol and heat, four different products are formed -- two by substitution (1-methoxy-2- methylcyclohexane and 1-methoxy-1-methylcyclohexane) and two by elimination (1-methylcyclohexene and methylidene cyclohexane (you will have to look that one up!)). What conditions could be used to change the outcome of this reaction by promoting the production of 3-methylcyclohexene as the product? [] Fulls
6. Draw the expected product when the following compound undergoes a double substitution reaction (HINT: a ring forms)? Na s HBr HBr (meso form) 7. For the following reaction, a) predict the major product and b) describe/explain the resultant stereochemistry of the product Br H20, acetone H2C CH2CH3 CH,CH2CH3
A) Reaction of 3-bromo-3-methylpentane and H2O and heat Draw the major product formed when the structure shown below undergoes substitution in H2O with heat. B)Substitution reaction of 3-bromo-3-methylpentane and CH3OH Draw the major product formed when the structure shown below undergoes solvolysis in CH3OH.
2. (10 points) Explain why the following deuterated 1-bromo-2-methylcyclohexane undergoes dehydrohalogenation by the Emechanism to give only the indicated product. observed not observed
8. Explain why the following deuterated 1-bromo-2-methylcyclohexane undergoes dehydrohalogenation by the E2 mechanism to give only the indicated product. Two other alkenes are not observed CH3 (CH, Br OCH, -CH Сн, H DH DH not observed observed
2. (10 points) Explain why the following deuterated 1-bromo-2-methylcyclohexane undergoes dehydrohalogenation by the E2 mechanism to give only the indicated product. н н wCH3 Осн, CH3 wCHs wCH Br H H D H not observed observed
1. Using the reaction of 2-chloro-1-methylcyclohexane with hydroxide ion, give the mechanism of Sn1 substitution. Complete the question as in question 1 2. Show how you might synthesise the following compounds given the indicated starting materials and anything else you need. In other words, show the reactions that would lead from starting materials to products. Assume that you can purify the products of each reaction. A synthesis may require more than one reaction (products of one reaction are used as starting materials in the...