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plant based antioxidants in fagara zanthoxyloides and cajanus cajan that compensate in the inborn defects of...

plant based antioxidants in fagara zanthoxyloides and cajanus cajan that compensate in the inborn defects of sickle cell diseases

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  1. Sickle cell anemia is a genetically inherited disease in which the “SS” individual possesses an abnormal beta globin gene
  2. Fagara zanthoxyloides roots have been analyzed for antiprotease and membrane stabilizing activity using a modified osmotic fragility technique to analyze membrane stabilization action.
  3. It has been discovered that the antisickling (and antiinflammatory) action of Fagara was due to its o-hydroxybenzoic acid constituent.
  4. Zanthoxyloides has shown sickling reversibility, appreciable increase in hemoglobin gelling time and improved rheological properties of sickling blood.
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