A small pilot study is run to compare a new drug for chronic pain to one...
A small pilot study is run to compare a new drug for chronic pain to one that is currently available. Participants are randomly assigned to receive either the new drug or the currently available drug and report improvement in pain on a 5-point ordinal scale. 1 = Pain is much worse, 2 = Pain is slightly worse, 3 = No change, 4= Pain improved slightly, 5 = Pain much improved.Use the Mann-Whitney U test to determine if the new drug is significantly better in improvement in pain with a 5% level of significance (i.e. one-sided).
New Drug: 2 4 1 3 5 2 5
Standard Drug: 2 3 1 1 4 3 5
9. What is the Critical Value
10. Define Group 1 to be those who received the New Drug. What is R1?
11. Define Group 2 to be those who received the Standard Drug. What is R2?
12. What is U1?
13. What is U2?
14. True or False: Reject the null hypothesis as the test statistic is less than the critical value.
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A small pilot study is run to compare a new drug for chronic
pain to one...
Bonus questions 51. A small pilot study is run to compare a new drug for chronic...
Bonus questions 51. A small pilot study is run to compare a new drug for chronic pain to one that is currently available. Participants are randomly assigned to receive either the new drug or the currently available drug and to report improvement in pain on a 5-point ordinal scale: 1 = Pain is much worse, 2 =Pain is slightly worse, 3 No change, 4 = Pain improved slightly, 5 = Pain much improved. A Mann-Whitney U test was performed to...
To test the effectiveness of a new drug designed to relieve pain, 200 patients were randomly...
To test the effectiveness of a new drug designed to relieve pain, 200 patients were randomly selected and divided into two equal groups. One group of 100 patients was given a pill containing the drug, while the other group of 100 was given a placebo. What can we conclude about the effectiveness of the drug if 62 of those actually taking the drug felt a beneficial effect, while 41 of the patients taking the placebo felt a beneficial effect? A)...
PRE-TEST QUESTION: 5. Seven people were selected for a study to compare pain relievers (Drug A...
PRE-TEST QUESTION:
5. Seven people were selected for a study to compare pain relievers (Drug A and Drug B). Each person was given both drugs, one after the other. There was enough time between the two drugs so that the first one did not affect the second one. The drug that was given first was determined randomly. The people in the study gave a pain relief score on a scale of 1 to 100. Data and an Excel analysis are...
A new chemotherapy drug is released to treat leukemia and researchers suspect that the drug may...
A new chemotherapy drug is released to treat leukemia and researchers suspect that the drug may have fewer side effects than the most commonly used drug to treat leukemia. The two drugs have equivalent efficacy. In order to determine if a larger study should be conducted to look into the prevalence of side effects for the two drugs, set up a Mann-Whitney U test at the alpha equals .05 level and interpret its results. Number of Reported Side-Effects Old...
Of the 93 participants in a drug trial who were given a new experimental treatment for...
Of the 93 participants in a drug trial who were given a new experimental treatment for arthritis, 57 showed improvement. Of the 90 participants given a placebo, 48 showed improvement. Use a 0.05 significance level to test the claim that improvement is independent of whether the participant was given the drug or placebo. Assuming independence between the two variables, find the expected frequency for each cell of the table. 1) Table of expected frequencies Improvement. No improvement Drug. ____________. ______________...
Of the 94 participants in a drug trial who were given a new experimental treatment for...
Of the 94 participants in a drug trial who were given a new experimental treatment for arthritis, 57 showed improvement. Of the 89 participants given a placebo, 51 showed improvement. 0.05 Significance 1) Assuming independence between the two variables, find the expected frequency for each cell of the table. Table of expected frequencies: Improvement. No improvement Drug ____________. _______________ Placebo__________. _______________ 2) Find the value of the x2 test statistic X2= _____ 3) use the given significance level to find...
2. A small study (n=10) is designed to assess if there is an association between smoking...
2. A small study (n=10) is designed to assess if there is an
association between smoking in pregnancy and low birth weight. Low
birth weight babies are those born less than 5.5 pounds. The
following data represent the birth weights, in pounds, of babies
born to mothers who reported smoking in pregnancy and those who did
not.
Mother smoked in
pregnancy
5.0
4.2
4.8
3.3 3.9
Mother did not smoke during pregnancy
5.1
4.9
5.3
5.4 4.6
Is there a...
3. A medical research team conducted a study to test the effect of a migraine drug....
3. A medical research team conducted a study to test the effect of a migraine drug. Of the subjects who took the drug 25% were pain-free after two hours. Of the subjects who took a placebo, 10% were pain-free after two hours. A claim is made that the percent of subjects who are pain-free after two hours is greater for the group who took the drug than for the group who took a placebo. You wish to test the claim....
In a pilot study with 20 subjects evaluating the use of a new drug to lower...
In a pilot study with 20 subjects evaluating the use of a new drug to lower resting heart rates (HR) of patients, the following data was recorded: Subject # Resting HR 001 72 002 88 003 71 004 87 005 64 006 77 007 79 008 59 009 77 010 68 011 78 012 89 013 91 014 81 015 85 016 75 017 69 018 75 019 77 020 81 Given that the average resting HR of the general...
3. The following contingency table represents a study to determine if a new drug is effective...
3. The following contingency table represents a study to determine if a new drug is effective in treating lower back pain. Participants were asked their pain levels two weeks after taking the two different treatments. No Pain Moderate Pain High Pain Drug 36 131 82 Placebo 12 194 157 a. How many of the patients had no pain or took the drug? (5) b. What percent of the patients had a high pain level? (5) c. What percent of the...
Bonus questions 51. A small pilot study is run to compare a new drug for chronic pain to one that is currently available. Participants are randomly assigned to receive either the new drug or the currently available drug and to report improvement in pain on a 5-point ordinal scale: 1 = Pain is much worse, 2 =Pain is slightly worse, 3 No change, 4 = Pain improved slightly, 5 = Pain much improved. A Mann-Whitney U test was performed to...
PRE-TEST QUESTION:
5. Seven people were selected for a study to compare pain relievers (Drug A and Drug B). Each person was given both drugs, one after the other. There was enough time between the two drugs so that the first one did not affect the second one. The drug that was given first was determined randomly. The people in the study gave a pain relief score on a scale of 1 to 100. Data and an Excel analysis are...
2. A small study (n=10) is designed to assess if there is an
association between smoking in pregnancy and low birth weight. Low
birth weight babies are those born less than 5.5 pounds. The
following data represent the birth weights, in pounds, of babies
born to mothers who reported smoking in pregnancy and those who did
not.
Mother smoked in
pregnancy
5.0
4.2
4.8
3.3 3.9
Mother did not smoke during pregnancy
5.1
4.9
5.3
5.4 4.6
Is there a...
3. A medical research team conducted a study to test the effect of a migraine drug. Of the subjects who took the drug 25% were pain-free after two hours. Of the subjects who took a placebo, 10% were pain-free after two hours. A claim is made that the percent of subjects who are pain-free after two hours is greater for the group who took the drug than for the group who took a placebo. You wish to test the claim....
3. The following contingency table represents a study to determine if a new drug is effective in treating lower back pain. Participants were asked their pain levels two weeks after taking the two different treatments. No Pain Moderate Pain High Pain Drug 36 131 82 Placebo 12 194 157 a. How many of the patients had no pain or took the drug? (5) b. What percent of the patients had a high pain level? (5) c. What percent of the...
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