Starting with benzene, show a sequence of laboratory reactions which could be used to produce the compound named in each part of this question:
A. m-Chloroethylbenzene
B. benzyl alcohol
A. First we carry out Friedel Craft Acylation in presence of anhydrous AlCl3. The acylated product is then chlorinated. Acyl group is a meta directing deactivating group. Thus the chlorine ion gets at the meta position. Next we reduce the acyl group to ethyl group by H2
B. Here again we carry out Friedel Craft reaction. But instead of Acylation we carry out Alkylation. Thus we obtain Toluene. This toluene is then oxidised to benzoic acid using KMnO4 . The last step is to convert benzoic acid to benzyl alcohol by reduction using H2
Starting with benzene, show a sequence of laboratory reactions which could be used to produce the...
Starting with benzene, give a sequence of laboratory reactions which could be used to prepare p-isopropylaniline. If separation of ortho, meta, or para-isomers is required, give evidence that it is feasible (e.g., boiling points, etc.)
of the 15) 4. Show a sequence of reactions that will produce the molecule shown below, starting with ethyne as the only organic starting material. Any other organics used must be made from ethyne, but you can use any inorganic reagents or solvents
66. Suggest a synthetic route by which one could produce the following compound from benzene. Provide all necessary reagents needed for each transformation. (10 pts) SO3H 66. Suggest a synthetic route by which one could produce the following compound from benzene. Provide all necessary reagents needed for each transformation. (10 pts) SO3H
(a) Devise a synthetic strategy to produce the following product starting from benzene: NH2 [M (b) Explain the mechanism of the electrophilic aromatic substitutions from part (a) and using Wheland diagrams, explain the regioselectivity of the reactions [M (c) Why is pyrrole aromatic, but not basic?
2. Starting from benzene, propose a step-by-step reaction sequence that would produce the following molecule (8 pts.) NO2 OH
17. Outline the reactions necessary to accomplish the synthesis of the following compound starting from benzene. Provide the necessary reagents/reactants and include the structure of intermediate organic products. Any additional organic starting materials used (excluding solvents) must not contain more than 3 carbons. You do not need to provide the mechanism of each reaction. ОН 18. Outline the reactions necessary to accomplish the synthesis of the following compound. Provide the necessary reagents/reactants and include the structure of intermediate organic products....
Show how you would synthesize each compound from benzene, toluene, or phenol using the following reactions: Reactions 1. Halogenation 2. Nitration 3. Sulfonation 4. Friedel-Crafts acylation 5. Friedel-Crafts alkylation 6. Oxidation of methyl group 7. Reduction of nitro group • Choose the starting material from the drop-down list • Enter the number(s) of the desired reactions in the order that you wish to use them without commas between • If a reaction is used more than once, enter its number...
Which method could be used to convert alkene 1 to alcohol 2? Please show the reaction mechanism. Question number 6 is also needed please. Part 2 - Word problems (4 pts each) 5. Taxol (compound 3) used in the treatment of several kinds of cancer, especially breast cancer. It was discovered from the bark of the Pacific yew tree. Each yew tree contains only a very small quantity, enough for just one dose for one person, so chemists started to...
Show by a series of reactions how you could prepare the following products from the indicated starting compound. Please, be sure to clearly indicate the reagents used in each step. Draw all intermediates a) 4pts used cyclohexanol as your starting materials. Освен -CECH from -OH b) 4pts Y c) 2pts
Starting with diethylmalonate, which sequence of reactions will give cyclopropane carboxylic acid? -0% OH Eto OEt 1. Excess KOEt 2. Br(CH2)5Br 3. H2O/H307, A O A. 1. Excess KOEt 2. Br(CH2)4Br 3.H2O/H307, A ОВ. 1. Excess KOEt 2. 1,1-dibromocyclopentane 3. H2O/H307, A Ос. 1. Excess KOEt 2. C5H9Br 3. H2O/H307, A OD Which is a mechanistic step in the sulfonation of benzene? SO3H fuming H2SO4 S SEO OH OH A B с D А B с D Which compound has...