using 1 mole of benzene and 1 mole of butane and, as carbon sources, design the synthesis of the following structure (what is its IUPAC name?) using organocuprate coupling reaction as the last step (no mechanism needed) (HINTS: the benzene can be transformed to an organocuprate; the butane can be transformed to an alkyl bromide; also consider whether the reactants of the last coupling step could be switched)
Using 1 mole of benzene and 1 mole of butane and, as carbon sources, design the synthesis of the ...
Using benzene as the only organic starting material, design a synthesis(no mechanism) for the following (use any other reagents that you need). Please disregard the orange box that is in the structure. Na
ii. Provide a synthesis of the following the compound below, using 1-propanol and carbon dioxide as your ONLY sources of carbon atoms. More than one step is required. You do NOT need to show the mechanism. You can use any other reagents that you desire. [6 marks]
Using propyne (structure shown) as your only source of carbon atoms, design a synthesis of the target molecule. You may use any organic or inorganic reagents you choose, but all the carbon atoms in the target must have come from propyne originally. Show the product of each step and the reagents needed for each step. Assume you have an unlimited supply of propyne.
Design a synthesis for 1-bromo-4-methyl-2-nitrobenzene using benzene as the starting material. You can handwrite everything. Please show the structures of the intermediates after each step as well as the reagents used.
Design a synthesis for 1-bromo-4-methyl-2-nitrobenzene using benzene as the starting material. You can handwrite everything. Please show the structures of the intermediates after each step as well as the reagents used. (NOTE: you can NOT use Friedel-Craft alkylation after Nitration.) ALSO, Professor said: ch3Br/FeBr3 --> Br/FeBr2 --> HNO3/H2SO4 OR Br2/FeBr2 -> CheCL/ALCL3 -> HNO3/H2SO4 would NOT work. Hint: need protecting group
Integrated Problem 09.64 Using acetylene and methyl bromide as your only sources of carbon atoms, propose a synthesis for the following compound: + En A Choose from the following list of reagents (A-H): 1) Br2 2) Excess H20 3) NaNH2 1) H2, Lindlar's catalyst 2) HBr 1) NaNH2 2) EtBr 3) Na, NH3 (1) 4) MeBr 1) NaNH2 2) EtBr 3) NaNH2 4) MeBr H 1) Na, NH3 (1) 2) MCPBA 1) NaNH2 2) EtBr 3) H2, Pt 1) H2,...
need help with the boxed bullet point. writing the chemical reaction scheme for the experiment. Synthesis of an Alkyl Halide: A Nucleophilic Substitution Reaction, Part I Pre-lab Assignment for Synthesis of an Alkyl Halide: A Nucleophilic Substitution Reaction, Part 1 1. From The Organic Chem Lab Survival Manual ( edition) by Zubrick • Review pages 201-204: Standard Reflux. • Review pages 127-140: Extraction • Review pages 164-189: Distillation, Simple Distillation. The Distillation Example, and The Distillation Mistake. 2. Read this...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Experiment 14 SN2: Synthesis of 1-Bromobutane Alkyl halides can be prepared from their corresponding alcohols via an acid catalyzed substitution reaction. The mechanism of these acid catalyzed substitution reactions are labeled as SNI (substitution, nucleophilie, unimolecular) and S2 (substitution, nucleophilie, bimolecular). Tertiary alcohols follow the Syl route, primary alcohols follow the S2, route and secondary alcohols can follow either path. Sth CyHe 81 CH? Br-CH e-OH- -C-OH OH Figure / Conversion of 1-butanol into 1-bromobutane by an Sp2 mechanism The...