Question

6. (2 pts) During project 2, you determined whether a LFER existed between the chemical shift value of the N H proton and substituent effects at X in the molecule below. The same experiment could be repeated, but instead varying substituents at Y. Assuming a LFER still exists in this case, predict the sign of p, and predict whether its magnitude would be greater than or less than ρ when X was varied. Give an explanation of your

LFER = Linear free energy relationship

Answer 1

Now NMR value in case of Electron Donating Substituents will be Lower and In case of Electron withdrawing Substituents NMR values will be High .

Let us lonsidue Fosmatien Buodut Ph tate n Rae mlhing a This Reaujien to Fund to be 9nutiat attauR ontor - The N dtom attauhed to áuisftued Benone. eauHien is Accle wakd by Eleutron Donaing áudusfuents (x) beause They uilh Valuts Reurion is betause Negatiue t-30 to o)

For correct Prediction of NMR value Last project details are Needed.