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List two classes of compounds (by class I mean molecules that contain a like functional group) th...

List two classes of compounds (by class I mean molecules that contain a like functional group) that are incompatible (in other words destroys the Grignard) with the Grignard reagent.

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Answer #1

Two classes of compounds that are incompatible with Grignard reagents are

1. CO​​​​​2​​​​H this is the carboxylic acid group

2. CONH-R this is the amides group

There are other class of compounds which are incompatible such as

-OH (alcohol group ) and NH​​​​​2​​​​ (amine group )

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