Answer:
a)
Design is completely randomized since it focuses on only the treatment (two different drugs) effects making it a single-factor experiment. The allotment of subjects is randomized.
b)
Design is matched pairs because by choosing each pair having the same value of the PCF, the effect of PCF, if any, is the same for both members of the pair and hence can be considered as identical entities. Consequently, the difference in the response variable for each pair becomes the statistic of concern.
c)
Design does not fit into any of the listed designs.
Clearly Design 2 is the best of the lot in terms of experimental error minimization. It recognizes the existence of PCF and also takes due care of that. The effect of PCF, if any, is nullified by pairing. Random assignment minimizes bias.
Two drugs are compared to see which of them is more likely to produce unpleasant side effects. Ea...
3. Two drugs are compared to see which of them is more likely to produce unpleasant side effects. Each of 100 subjects is given the two drugs on different occasions. The results are tabulated below Nausea with drug B 38 10 No nausea with B Nausea with drug A No nausea with A 50 Let pij denote the probabilities that a patient has a response in the ijth cell. For instance p12 denotes the probability that a patient experiences nausea...
Please donot copy from other answers 3. Two drugs are compared to see which of them is more likely to produce unpleasant side effects. Each of 100 subjects is given the two drugs on different occasions. The results are tabulated below Nausea with No nausea Nausea with drug3wit Nausea with drug A No nausea with A 38 10 2 50 Let pij denote the probabilities that a patient has a response in the ijth ce. For instance p12 denotes the...
Although the sample sizes are not large for some of the examples below, you can use chi-square ap- proximations to calculate p-values for the likelihood ratio tests. 3. Two drugs are compared to see which of them is more likely to produce unpleasant side effects. Each of 100 subjects is given the two drugs on different occasions. The results are tabulated below Nausea with drug B 38 10 No nausea with B Nausea with drug A No nausea with A...