Question

(3 pts) Quantitative characterization of renal clearance, use words to describe equation 16: (16)

Answer 1

In above equation we knows that

${\dot {m}}$ is the mass generation rate of the substance or drug ,t = dialysis time, V =volume of distribution or total body water, K = clearance, C= concentration, C_o = initial concentration of the substance or drug

Above equation tells the relationship between mass removal and clearance. If mass generation kept constant then the concentration and clearance are inversely proportional to each other.