Question

mechanism predicts that 4b should be formed. may be nepiu to 61 Several natural products have been isolated from the flowering plant Sarcostemme acidum, which has been used in folk medicine as a cough suppressant During efforts to make these compounds in the laboratory, it was discovered that one of the natural products is readily converted into another one of the natural products in a cyclization reaction that occurs upon treatment with a strong acid.10 A similar cyclization is shown below idently the sequence of arrow pushing patterns in the following mechanism for the conversion of compound 1 to compound 2 H,O CH CH, Ph CH Ph Compound Ph TSOH -HC Compound 2 -o-H

Answer 1

: он Ts CH 3 fh The loe pr on o vm on Ph turn 'on g ๑ ea vi The double bond act a ming a 8euondo eliminalion er molede The lone pair, SA o reachoming oek the alkane acon