Question

1 9. Arrange the following in ng compounds in increasing (weakest to strongest) order of basicity. NH2 NH2 NO2 E. None of the above What is the product of the following sequence? 10. H3C CH3 OH он Na V. A I What is the major product for the following Reaction? 11. Pd(OAc)h PPhy Et N NO2 NO2 NO2 C.Ⅲ A. I D. IV V. 12. Predict the product for the following reaction. Br 1. NaNs 2. LiAIH4 3. H20

Answer 1

owing compounds in increasing (weakest to strongest) order of basicity. Pyrrole (IID is least beasic as lone of electron on N atom is involved in conjugation the doble bond in the ring. Pyridine (III) is more basic than pyrrole because the lone of electron on N atom in pyridine is not involved in conjugation of aromatic ring. Benzyl amine (IV) is most basic as the lone of electron on N atom is available for donation NH2 NH2 NO2 1V p-Nitro aniline (1) is less basic than benzyl 111 Il <\ C. A. amine because of electron withdrawing effect of N02 None of the above E. What is the product of the following sequence? 10. MgCi H Cl CH3 Et20 H30 Et20 + CH3OH он OH H3C Na V. A. I 11. What is the major product for the following Reaction? Pd-catalyzed Heck coupling Pd(OAc)h NO2 PPhs Et NO2 NO2 NO2 NO2 A. I D. IV V. 12. Predict the product for the following reaction. In the first step Br to azide and in the next step azide is reduced to amine by LiAIH4 Br 1. NaN 2. LIAIH4 3. H20