predict the product 1. (12 pts) Predict the product for the following transformation. OH OH 유 1.H2OH' HO 2. KH, 18-c-6, THF OH OH Br Ph OH OBn O 1. H20, H HO 2. O 、Me , cat. H+ Me 1. (1...
1. (3 pts) Predict the product for the following transformation. Me 1. KH. 18-crown-6, THE 2. Me Me Me Br Me
Predict the product: H20, H2SO4 (cat.) THF. reflux H,O, H,SO. (cat.) THF, reflux
(10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO (10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO
1. Predict the major product of the reaction. Clearly indicate stereochemistry, if necessary (3 pts) Ph H2 Lindlar cat. hexanes Me 2. Provide reagents to achieve the shown multi-step transformations. (6 pts) Br CH 3. Draw a detailed arrow-pushing mechanism for the following transformation. (4 pts) OME B OMe Me Me NaOH H2O2 Me Me H
1. Predict the major product of the reaction. Clearly indicate stereochemistry, if necessary (3 pts) Н.С. Me 1. 9-BBN-H THF 2. NaOH H2O2 Me 2. Provide reagents to achieve the shown multi-step transformations. (6 pts) H Ph OH Ph. Br Br
PREDICT THE PRODUCt: 1. NaNH2 H₂ H-CEC-CH2 CH2 CH3 2. CH3CH2Br Lindlar cat. 1. Sia BH-THF 2. H2O2, H20
Predict the major product for the following reaction. Na,Cr,07. OH 1) PB1z,Br2 2)H, H2SO4, H20 O Br o TH Br
CH OH HO 100% Me CO-Et HB 2 H-O EtOH AcOH 68% Br T8 Me 77% CH 0H 2 10% HCI in MeCN 1) TsCllpy 2) Nal LDA H (cat.) Me Me 75% CH-OH CH2 Me (8 6 Draw wedge/dash drawing of the following Fischer projection scheme 1-8 and assign the stereocenter(s) R or S absolute configuration
Predict the product(s) for the following reaction. 1. excess LiAIH 2.H20 Edit Predict the product for the following reaction. 0 Br Mg/ether 1. H 1 H 2. H20 12 Edit Predict the major product for the following reaction. -OH 1. TsClipyridine 2. CH CH ONa 12 Edit Predict the product for the following reaction. NaH OH Br heat ? Edit
1) R'-MgBr in THF 2)H,o NaH Ho or OH PAA X2. H20 1) Hg(OAc)2, R'OH 2) NaBH4, NaOH, H20 Os0 NaHSO, H2O I) 2)CH, SCH HyIO HBr ROOR 1)BH3. THF 2)H202, NaOH, H2O Mg, THF PBr3 NaOH )OTHF 2) H30 CrOj. H,SO, 1) NaH 2)RXDMF "О-R DMF PCC DCM ) THF 2) H3O+ SOCI pyridine Li Hexanes