Question

I a Write the stracture of b. (R )-2-butanol, shown below is converted to a chiral iodide by reacting with sodium iodide. Show the mechanism involved in the reaction and state configuration of the chiral product. 2. Show the products of the following reactions and identify the number of possible stercoisomers that can be produced CH, CH,CH- CH, 1.BH, 2. NaOH, H202 3. Cortisone is a natural steroid that can be isolated from the adrenal cortex. It has ant- inflammatory properties and is used to treat a variety of disorders. The structure of cortisone is shown below (a) Identify all of the chiral centers in the structure of cortisone. (b) Assign the appropriate (R) or (S) designation for the configuration of each chiral center in cortisone

Answer 1

1 9 Yomo -ys-dichloro heptane b) SN -2-butene on tan approach to e, cert oodati 워Dewi (R-)- R--2-odabuteine sioe berause orésocutien Ats Planar and s- looeloltee equa amount (so:sa)