Design a Synthesis: Show both the retrosynthetic analysis, as well as the forward synthetic scheme. The overall transformation may require more than one step. Design a Synthesis: Show both t...
For any two of the molecules below, outline both a retrosynthetic analysis and a forward synthesis with reagents. Each of your building blocks should not incorporate more than five carbon atoms of the target molecule. (Note: your syntheses do not need to be stereoselective) COH OH [20 marks]
Please answer both When performing a retrosynthetic analysis for the desired synthesis below, what is the best question to ask first? Br CH3-C=CH Br To what functional group can two adjacent bromine atoms be added? Which alkyl halide is needed for the synthesis? How can I deprotonate an alkyne? What reagents are needed to alkylate an alkyne? What is most likely the initial retrosynthetic disconnection of the target molecule in the given synthetic transformation (i.e., the last step of the...
9. P ropose a multi-step synthesis to accomplish the overall transformation shown below (make the molecule on the right starting with the molecule on the left). Show all necessary reagents and products for each forward step. [It is not necessary to show any mechanisms.] OH 10. Propose a multi-step synthesis to accomplish the overall transformation shown below (make the molecule on the right starting with the molecule on the left). Show all necessary reagents and products for each forward step....
2. (4 pts.) Provide a reasonable synthesis for the following transformations. More than one step may be needed. Show all reagents and synthetic intermediates.
Propose a synthesis for the following transformation. More than one step is required. NO2 НО,
How would you carry out the following synthetic transformation? Show the synthesis step by step including all of the major intermediate structures. Other reagents may be used as needed. Several steps OH ? (The only source of Organic Compounds)
2. (5 pts.) Show hoe the following transformation could occur. The reaction may require more than 1 step. Show any intermediates/reagents but no mechanisms
4. Propose a synthetic pathway for the following reaction (there may be more than one correct way), then show the mechanism for each step (Hint: To save time make sure your synthesis pathway is absolutely coret before you work on mechanism) но Br
1) Show how you would make the following synthetic transformations. More than one step may be required. a) Benzene to 3,5-dibromo-1-ethylbenzene b) benzene to benzylamine (aminomethyl benzene, not aniline) c) benzene to benzonitrile d) methyl orange from sulfanilic acid
Use retrosynthetic analysis to design a synthesis on paper for the transformation of 2-chloro-3-methylbutane into 3-methylbutanal as shown below. You'll need six of the following reagents. Order the correct ones in order 1-6.The one you don't use will be number 7 through 10. But order the 7+ ones in analagous order to the synthesis. For instance, if your first step is a zaistev elimination, and you have a bulky base and a nonbulky base, then reagent number 7 should be the bulky base. If your...