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11. Speculate why adenosine, rather than another large molecule, is used often as a cofactor in a nucleotide-binding fold of
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The nucleotide adenosine is present in cofactors that catalyse many basic metabolic processes such as acyl, methyl, and phosphoryl group transfer, as well as redox reactions. Adenosine-based cofactors can be acted as interchangeable adaptors that allowed enzymes and ribozymes to bind new cofactors through small modifications in existing adenosine-binding domains, which had originally evolved to bind a different cofactors.

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