Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 3-phenyl-3-pentanol. (Click and drag the appropriate image to the correct position in the following reac
tions.)
The concept used to solve this problem is by using the given reagents, reactants, the desired product will be formed. So, label it exactly in the given boxes in order to form the exact product.
Formation of alcohol using ester, carbonyl compounds with the Grignard reagent. Here, the final product is 3-phenyl-3-pentanol.
Reaction of aldehydes or ketones with a Grignard reagent followed by the hydrolysis forms a new alcohol.
Esters forms tertiary alcohol when reacted with two equivalents of Grignard reagent.
Reterosynthesis is as follows:
The synthetic reaction for the route 1 is as follows:
Reterosynthesis is as follows:
The synthetic reaction for the route 2 is as follows:
Ans:The best compounds that are used for the synthesis of 3-phenyl-3-pentanol are as follows:
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and...
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 2-phenyl-2-propanol. (Click and drag the appropriate image to the correct position in the following reactions.) Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either...
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 3-methyl-3-pentanol. (Click and drag the appropriate image to the correct position in the following reactions.) Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either...
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 2-methyl-2-butanol. (Click and drag the appropriate image to the correct position in the following reactions.) Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either...
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 3-methyl-3-pentanol. (Click and drag the appropriate image to the correct position in the following reactions.)
43. Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 1,1-diphenylethanol. (Click and drag the appropriate image to the correct position in the following reactions.) Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made...
tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of Grignard reagent, or from a ketone and one mole of Grignard reaction .Use retrosynthetic analysis to suggest one path of each type to synthesize 3-phenyl-3-pentanol. Route 1 -----> ester (draw here) + Grignard (draw here) -----> H3O------> 3-phenol-3pentanol Route 2 --------> Ketone (draw here) + Grignard (draw here)
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 1,1-diphenyl-1-propanol. (Click and drag the appropriate image to the correct position in the following reactions.)
21-Ketones are easily reduced to secondary alcohols. b- Primary CH, CCH, a-Secondary alcohol alcohol C- to acetaldehyde acid d-to carboxylic 22-Ozonolysis of alkenes yields aa-ketones if one of the unsaturated carbon atoms is disubstituted b-alcohol C-carboxylic acid d-alkane 23-Aldehyde C=0 is more polarized than ketone C-0 because a-As in carbocations, more alkyl groups stabilize + character b-Ketone has more alkyl groups, stabilizing the C=0 carbon inductively cc- due to a and b d- none of the above 24-Aldehydes and unhindered...
a. Alkenes with electron withdrawing groups are good dienophiles-True/False b. Wolfkishner reaction is helpful to convert an ester to alkane. True false c. Tertiary alcohol will be formed by the reaction between a ketone and Grignard reagent True/ false d. A cyclic conjugated compound with 6 pi electron is aromatic- True/ False e. Addition of CO; to Methyl magnesium bromide is a nucleophilic addition Truel false f A good protecting group should be cleaved during the progress of the reaction-True...
help with 23 HAPTER 14: ORGANOMETALLIC COMPOUNDS TWO common solvents for Grignard reagents are: 1) ethanol and diethyl ether. 2) diethyl ether and tetrahydrofuran (THF). 3) tetrahydrofuran (THF) and toluene. 4) water and ethanol. What is the product of the following reaction? CH, CH. CHCH.CH - ether 2) 2-ethyl-1-pentanol 2) 2-ethyl-1-butanol 3) 3-pentanel 4) 3-aethyl-1-pentanc: The reaction of benzyl sagnesius bromide (C.HSCHMB) with acetaldehyde (CHC40) followed by hydrolysis yields: 1) 1-phenyl-1-propanol 2) 1-phenyl-2-propanol 3) 2-phenyl-2-propanel 4 .-ghen -propane: mo synthesize...