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Practice Worksheet 8: Alkyne 3. Alkynes are deprotonated (remove H) by strong base leg.. NaNH then can undergo SN2 substitution with electrophiles such as alky in the missing boxes for each alkylation. The first reaction is shown as move H) by strong base lee Na Hal to give acetylide ions. These ution with electrophiles such as alkyl halides and alkyl sulfonates. Fill en alkylation. The first reaction is shown as an example of an alkylation a. NaNH, NH3 b. add: CH,Br CHE a. NaNH, NH3 b. add a. NaNH NHA b. add: a. NaNH, NH3 b. add HECH OTS a. NaNH2, NH3 b. add: HCo- H.CO a. NaNH , NH, b. add: Page 2 of 4

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Practice Worksheer 8: Ale 3. Alkynes are deprotonated (remove H) by strong base (eg. NaNH) to give acetylide ions. These then can undergo SN2 substitution with electrophiles such as alkyl halides and alkyl sulfonates. Fill in the missing boxes for each alkylation. The first reaction is shown as an example of an alkylation a NaNH NH CH b add: CH,Br a NaNH NH b add Br a NaNH NH b add H H Br a NaNH. NH Нас- b add HyC H a. NaNHg, NH b add Нсо- Нсс a NaNHg, NH b. add Br Page 2 of 4