2. Design a synthetic route for the following conversion of methylcylohexane into compound A using retrosynthesis a...
1. Draw the line structures and arrange the following substrates in order of increasing SN2 reactivity with NaCN: Bromoethane, 1-chloro-3,3-dimethylpentane, 1-chloro-2,2-dimethylpentane, and 2-bromo-2- methylpentane. (1 pt) 2. Design a synthetic route for the following conversion of methylcylohexane into compound A using retrosynthesis analysis. You may use any other reagents that you need. (1 pt) 3. Predict which of the following two compounds will undergo an E2 reaction more rapidly in presence of EtONa/EtOH. Draw the reaction product(s) and the mechanism...
2. Design a synthetic route for the following conversion of methylcylohexane into compound A using retrosynthesis analysis. You may use any other reagents that you need. (1 pt)
Retrosynthesis. Propose the most efficient synthetic route to make the following compound starting from the indicated reagents and any other reagents, clearly identifying the reaction conditions at each step and the structure of the intermediates formed. "Note: This will require more than 3 steps BrMg
yeah Retrosynthesis. Propose the most efficient synthetic route to make the following compound starting from the indicated reagents and any other reagents, clearly identifying the reaction conditions at each step and the structure of the intermediates formed. *Note: This will require more than 3 steps HH BrMg
Retrosynthesis. Propose the most efficient synthetic route to make the following compound starting from the indicated reagents and any other reagents, clearly identifying the reaction conditions at each step and the structure of the Intermediates formed. *Note: This will require more than 3 steps BIO o 3 by BrMg
PROBLEM o Using retro-synthesis or synthetic design propose a route for the following conversion. dando o Draw all the forward reactions to complete the work (synthesis); o Starting with 1-pentyne synthesize 1,1-dichloro-cis-2,3- dipropylcyclopane using any alkyl iodide and any other necessary inorganic or organic reagents. I-penye
Propose the most efficient synthetic route to make the following compound starting from the indicated reagents and any other reagents, clearly identifying the reaction conditions at each step and the structure of the intermediates formed. Propose the most efficient synthetic route to make the following compound starting from the indicated reagents and any other reagents, clearly identifying the reaction conditions at each step and the structure of the intermediates formed. *Note: This will require more than 3 steps* ohin 3...
6. Predict which of the following two isomers (cis- or trans-) will undergo an E2 elimination under the treatment with EtoNa in EtOH more rapidly. A) For the explanation of the reaction rate, draw chair conformations for each isomer, determine which conformation is more stable . B) Draw the major product and the mechanism of the reactions. CI cis-isomer trans-isomer
12. Design a synthetic route for the following compound free of other isomers. You do not need to write mechanisms. Assume you have access to benzene, isopropyl alcohol, acetyl chloride, and any inorganic reagents (10 points).
2. G Give a detail ive a detailed synthetic route to A. using starting material with 3 or fewer carbons. ed arrow pushing mechanism for each reaction in the route. (33pts) A.