Question

Protein folding and lipid-bilayer formation result in decreased entropy for a protein molecule and bilayer components. The decrease entropy of the surrounding entropy is balanced by a large increase in the OTemperature Salt solutions Pressure Water molecules Water's ability to dissolve a wide variety of molecules is important, but more important is the hydrophobic effect, which drives the aggregation of nonpolar molecules and plays a role in the folding of proteins and formation of lipid bilayers. What forces drive the hydrophobic effect? View Available Hint(s) Decreased entropy of water is the largest driving force Water repels the hydrophobic molecules. Increased entropy of water is the largest driving force. Hydrophobic molecules are attracted to each other

Answer 1

Question 1:

Protein folding is exothermic, hence it increases temperature of the surroundings.

Option 1 is correct.

Question 2:

Hydrophobic interaction is the main driving force in protein folding. Hydrophobic molecules are attracted to each other.

Force present between hydrophobic groups ( nonpolar) are van der Waal force.

Due to this water molecules have more possibility to attract other water molecules. Thus entropy of the water increases.

$\Delta$G = $\Delta$ H - T $\Delta$S

Thus , free energy decreases.

So, increased entropy of water is the main driving force. Option 3 is correct.