Question

Retrosynthetically design a synthesis from readily obtainable starting compounds up to a max of 8 Carbons. Have atleast 1 carbon-carbon bond forming reaction for each synthesis. Show every step, synthon and synthetic equivalents, and functional group conversions (and additions, disconnections).

Also;

- Don’t need the forward reaction, but use all proper conventions.

- Phenyl = Ph (six Carbons)

- The Disconnection needed is specified.

A)

B)

(a) 1,3 (Aldol) (b) 1,3

Answer 1

A> cyclopeutenone Retrosynthesis Reto Al dol HO Syuthe he equivaleut $ynthou OH Syuthesis H20 92,4 Na oH Soluton H Retrosyuthesis syntue tic equi valeut Syutuous Spnthe sls BY n- BuL SH 78 PTS ate/A Hg ce2 cacDz H20