20. Design a synthesis to perform the following transformations. Show all reagents and synthetic intermediates. Abo...
19. Give the major organic product of each Robinson Annulation reaction. NaOM, MOH 20. Design a synthesis to perform the following transformations. Show all reagents and synthetic intermediates. Above each arrow is the number of steps each synthesis can be performed in, but you can use as many steps as you need. i cili - X why ОMe Meo
Provide reagents and intermediates to carry out the following synthetic transformations. Synthesis Questions: Provide reagents and intermediates to carry out the following synthetic transformations ( 6-8 marks each) A)
Using any necessary reagents, show how the following synthetic transformations may be achieved. Give reagents and conditions for each step. Include all synthetic intermediates (compounds produced during the course of multi-step synthesis). As always, consider major products produced throughout the entire synthesis. a. он
7. Provide a synthetic procedure for the following transformations. Be sure to show all major intermediates and reagents. Give a brief explanation for each problem using complete sentences why you came to your answer. No explanation = no credit ОН HO b.
Question 6.(continued) Subsequent steps in this synthesis of morphine are illustrated in the following scheme. (b) MeO Meo NHMe но COOMeO, он MeO OMe но. Meo NMe NMe но Codeine Morphine Propose a synthetic route to compound F including all reagents and isolated intermediates. Hint: the methyl ester should be made from the corresponding acid using mild conditions. (0) from compound E (several steps), 17) Write the retrosynthesis of codeine leading back to compound G, clearly indicating the disconnections and...
Synthesis 1. The following transformations cannot be performed in one step. Provide a sequence of reactions to convert the "starting material" to the "product. Show all the reagents and synthetic intermediates. You can use any additional carbon sources if needed, but you must use the starting material given. "он но 1 Он он Br 1 K
Synthesis The following transformations cannot be performed in one step. Provide a sequence of reactions to 1. convert the "starting material" to the "product." Show all the reagents and synthetic intermediates You can use any additional carbon sources if needed, but you must use the starting material given. H но он Br 1
Synthesis 1. The following transformations cannot be performed in one step. Provide a sequence of reactions to convert the "starting material to the "product." Show all the reagents and synthetic intermediates. You can use any additional carbon sources if needed, but you must use the starting material given. Br -ОН Br
Propose a suitable synthetic route to perform the following transformations. List the reagents and conditions at each step and the structures of the precursors. H2C N H3C- ОН НЫС CH3
4. Synthesis. Show how to perform the following transformation. Show all reagents and intermediates. Several steps may be necessary. (1 pt) Ask yourself: 1) Is there a change in the carbon skeleton? 2) Is there a change in the position or identity of the functional groups? OH phenol