Question

Here is a molecule. Do a retro synthesis (reaction scheme) on the molecule and go all the way back to produce the molecule until you can't go back anymore (think benzene or carbon). You can use any source and synthesis/reaction to produce the molecule above. Some notes about the molecule:

H3CO

I would say start by writing down all the one step reactions you know that would make the molecule without considering from where the starting material comes. With some luck you should be able to come up with a half dozen reactions.

Here are my notes on this molecule:

> Initially my thoughts is that I see some double bonds which indicates to me Wittig reactions? Is stereochemistry relevant here? Like the R group on the yilde being a phenol or a CH3 and therefore producing the E or Z product?

> Other things that jump out at me I see the ether group their so I would assume the last step in the retro synthesis would be to make an ether with alcohol or an alkyl halide?

> Also their is a ketone their because of the wittig reaction and so I guess we can do alpha/beta aldol?

> Something else is the benzene group which has a methyl group and is therefore going to be o/p director but it can be oxidzed into an ethyl group?

Answer 1

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