Question

Catherine Garber is a 42-year-old office manager admitted to the hospital’s intensive care unit. She was first seen in the emergency department with severe edema, headache, nausea and vomiting, and a rapid heart rate. She reported an inability to pass more than minimal amounts of urine in the past two days. Her son, who drove her to the emergency department, reported that she had missed work for several days and seemed confused and unusually tired. Laboratory tests revealed elevated serum creatinine, BUN, and potassium levels. After learning from her medical history that Mrs. Garber had begun taking penicillin in the previous week, the physician diagnosed acute kidney injury, probably caused by a reaction to the medication. Mrs. Garber is 5 feet 3 inches tall and weighs 125 pounds 1. 1.Describe the probable reason for Mrs. Garber’s inability to produce urine. Is her reaction to penicillin considered a prerenal, intrarenal, or postrenal cause of kidney injury? Give examples of other medical problems that can cause acute kidney injury.

Answer 1

Probable reason may be drug induced acute interstitial nephritis as patient ha history of penicillin intake

It is intrarenal cause of acute kidney injury as there is damage to structure of kidney i e interstitium of kidneys

Other medical problems that cAn cause aCute kidney injury are bladder cancer, cervical cancer as they may block ureters therefore urine excretion is obstructed.

Lupus and glomerulonephritis may cause aki as there is destruction in kidney structure.