Question

3. Explain why the set of fitnesses wAAw Aa (a) disease. 0 describes lethal recessive w, waa a use the Fisher-Haldane-Wright equation to derive the following (b) For such a disease, difference equation describing the time-evolution of pPn, the adult frequency of allele A: 1 Pn+ = 2 P (c) Verify by substitution that the expression n1 Pn n 2 is the solution of the difference equation from (b), where po = 1/2.

Answer 1

Pht 2-Pn Po PL 2- Po PI 2-Y, h L P2 2-P 4 h 2 4 3/4 also td Stnuary htl nt2 Verifed Po O t 2 Veft 2- (Sone) PI hai 3 Neihuy he 2 Veufe ns 3 Veuh Valu a all the