Question

Show two methods to synthesize each alkene: a one-step method using a Wittig reagent, and a two-step method that forms a carbon-carbon bond with an organometallic reagent in one of the steps. а. b, Problem 21.22 Draw the product formed when CH,CH,CH,CH,NH, reacts with each carbonyl compound in the presence of mild acid. -сно а. Problem 21.25 What carbonyl compound and amine are formed by the hydrolysis of each compound? a.

Answer 1

Wittigi Phypit RX & Clyn Buli [on 8 -cth] Here R=CH₂ PhyP =CH₂ on Step 2 i and Method ; Grignard Reagent H2O acid + birting) es pot an eco =o+m-en n omico eie OTPPh Phyp=Chiyo - Grignard : OMOBY OH 8 8+ K CHATO CHON H₂SO4/H+

y cho + CHICH, CH₂ CHINH 014 o-v- н-соо То) + мнен,си, сисH, N-CH(, CHCH Z-I | Htlacid c=N -Сн, -ін,--сч, но + (о ін, снен, н, сH, NHси, сисHсч, Hlacid р-си, се си, Сн, NH- CHUC- А + но Rearrangemal ОН I NHCH₂ CH₂ CH₂CH, o ft,си, си,сни, 7 Mt/acid му сну си, син, a + ио NHCH, CHChichy Rearranyent І: 2 TY CHO + HN b) Y NH too - NH tos