Question

What is the catalytic triad of chymotrypsin, a type of serine protease? the enzyme-cofactor-intermediate complex the amino acids serine, histidine, and aspartate the amino acids cysteine, histidine, and aspartate the enzyme-cofactor-substrate complex the amino acids serine, histidine, and glutamate

Answer 1

Concepts and reason

This problem is based on the concept of amino acids found in the catalytic triad of chymotrypsin.

A catalytic triad is a type of catalyst which functions at the active site’s center of various enzymes like protease.

Fundamentals

Chymotrypsin is a serine protease. It is an enzyme which regulates the breakdown of proteins and polypeptides.

Catalytic triad is a combination of amino acids which function altogether at the center of an active within an enzyme. it contains usually three amino acids. Therefore, it can neither be an enzyme-cofactor-intermediate complex nor the enzyme-cofactor-substrate complex.

The correct definition chymotrypsin is given below:

Catalytic triad of chymotrypsin is,

‘the amino acids serine, histidine and aspartate.

Ans:

Catalytic triad of chymotrypsin is,

‘the amino acids serine, histidine and aspartate.