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Concepts and reason

In organic chemistry, retrosynthetic analysis is one of the problem-solving techniques that is used to find the structures of the starting materials (reactants) by analyzing the key functional groups that exist in the structure of the target (product).

Fundamentals

Retrosynthesis (Retrosynthetic Analysis)

Retrosynthetic analysis is used for designing the synthesis of organic compounds. In this analysis, the planning of organic synthesis takes place by disconnecting the target molecules into precursors.

Target molecule
Precursor molecules
=
Starting materials
This arrow indicates can be made from.

Crossed Aldol Reaction

Crossed aldol reaction is an organic reaction in which one of the substrates contains any alpha hydrogen atom with a sterically unhindered carbon atom. An enolizable aldehyde or ketone reacts with another aldehyde or ketone in the presence of the base/acid, giving the crossed aldol product (alpha-beta unsaturated carbonyl compound).

НО

The structure of the organic molecule is given below:

hydroxyl functional group, alcohol
carbonyl functional group, ketone

Reaction Mechanism:

OH
ОН:
HO
target molecule
starting material 1
Ulyai
starting material 2

Ans:

OH
from
|
+
target molecule
starting material 1
starting material 2

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