Question

Dalcetrapib is a cardiovascular disease-fighting agent that inhibits the cholesteryl ester transfer protein (CETP), thus increasing high-density lipoproteins (HDLs). Starting from benzene and the provided reagents, complete the most efficient, high-yielding three-step synthesis of the dalcetrapib analogue shown below. Drag the appropriate items into the bins. Note that each bin should hold only one item, and not all reagents and structures will be used. (Stoichiometry is omitted.)

Answer 1

please click this:.... https://dl.dropbox.com/u/48904174/answer.PNG

Answer 2

left to right 1 .benzene ring 2.HNO3,H2SO4,heat 3.Ph-NO2 4.Fe,HCL:NaOh,H2O 5.Ph -NH2 6. the cyclohexane that has cl bond o it

Answer 3

Dalcetrapib is a cardiovascular disease-fighting agent that inhibits the cholesteryl ester transfer protein (CETP), thus increasing high-density lipoproteins(HDLs). Starting from benzene and the provided reagents, complete the most efficient, high-yielding three-step synthesis of the dalcetrapib analogue shown below. Drag the appropriate items into the bins. Note that each bin should hold only one item, and not all reagents and structures will be used. (Stoichiometry is omitted.) Reactant Reaent 1 (benzene) Reagent3 Step 1 product>Step 2 product> Reagent 2 HNO3, H2SO4, heat 1. Fe, HCt 2. NaOH, HO O2N H2N (dalcetrapib analogue Ha NaBHi, M,O он Na, NH3, CH3OH