Question 3 (a) Arange the following compounds in order of decreasing reactivity with nucleophiles (ie. most...
Question 3 (a) Arange the following compounds in order of decreasing reactivity with nucleophiles (ie. most reactive compound first). Explain your reasoning. (6 marks) C Me Me OMe OMe F C NMez Me Me Answer TWO parts from (i)-(iii) (7 marks each). (b) Give mechanisms for the following reactions and use them to explain the different (i) reaction outcomes. LIAIH он Me OMe Me LIAIH NMez Me NMeg Me (i) Give mechanisms for the following reactions and use them to reaction outcomes. explain the different Me HO Me Me кОН/ Но Me Eto. Me Me H/H2O EtO. OH (iii) Phenyl methyl ketone can be prepared by the reaction of lithium dimethylcuprate (Me,CuLi) methyl lithium (MeLi) cannot be used in place of Me2CuLi to carry out this transformation mechanism for this reaction. Explain why as shown below. Give a Me CuLi Ph Me Cl Ph
Question 3 (a) Arange the following compounds in order of decreasing reactivity with nucleophiles (ie. most reactive compound first). Explain your reasoning. (6 marks) C Me Me OMe OMe F C NMez Me Me Answer TWO parts from (i)-(iii) (7 marks each). (b) Give mechanisms for the following reactions and use them to explain the different (i) reaction outcomes. LIAIH он Me OMe Me LIAIH NMez Me NMeg Me (i) Give mechanisms for the following reactions and use them to reaction outcomes. explain the different Me HO Me Me кОН/ Но Me Eto. Me Me H/H2O EtO. OH (iii) Phenyl methyl ketone can be prepared by the reaction of lithium dimethylcuprate (Me,CuLi) methyl lithium (MeLi) cannot be used in place of Me2CuLi to carry out this transformation mechanism for this reaction. Explain why as shown below. Give a Me CuLi Ph Me Cl Ph