Unsymmetrical ethers can be made by the Williamson synthesis, in
which an alkoxide ion reacts with an alkyl bromide. Draw the
structure of the alkoxide and the alkyl bromide needed to produce
2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below.
Show charges where appropriate.
Williamson ether synthesis is a reaction between an alkoxide and a primary alkyl halide by mechanism to produce both symmetrical and unsymmetrical ether, where alkoxide acts as a nucleophile.
General reaction mechanism:
In mechanism reactivity order of the alkyl halide is
.
Character of alkoxide is less important in this reaction.
Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with...
Unsymmetrical ethers can be made by the Williamson synthesis, in
which an alkoxide ion reacts with an alkyl bromide. Draw the
structure of the alkoxide and the alkyl bromide needed to produce
2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below.
Show charges where appropriate.
Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and the alkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether),...
Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and the alkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below. Show charges where appropriate. alkoxide alkyl bromide ether + Br
Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and the alkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below. Show charges where appropriate.
Unsymmetrical ethers can be made by the Williamson synthesis, in
which an alkoxide ion reacts with an alkyl bromide. Draw the
structure of the alkoxide and the alkyl bromide needed to produce
2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below.
Show charges where appropriate.
Unsymmetrical ethers can be made by the Williamson synthesis, in
which an alkoxide ion reacts with an alkyl bromide. Draw the
structure of the alkoxide and the alkyl bromide needed to produce
2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below.
Show charges where appropriate.
Draw the structure
Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and the alkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below. Show charges where appropriate. alkoxide alkyl bromide ether Br
1. Unsymmetrical ethers can be made by
the Williamson synthesis, in which an alkoxide ion reacts with an
alkyl bromide. Draw the structure of the alkoxide and the alkyl
bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl
ethyl ether), shown below. Show charges where appropriate.
2. What nucleophile could be used to
react with butyl iodide to prepare the following compound?
Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and thealkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a. t-butyl ethyl ether), shown below. Show charges where appropriate.
1. Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and the alkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below. Show charges where appropriate.HINT:The reaction involves an SN2 attack of the alkoxide on the alkyl bromide, displacing the bromide ion.R1O- + R2Br --------> R1-0-R2 + Br-What are the alkyl groups found in the ether? One alkyl group will come from...