Why does compound 1 undergo facile substitution with NaCN, but compound 2 does not? Br Br...
1. Which two of the following halides CANNOT undergo substitution reactions? Circle your answers. (4 pts) Br CI Br CI Br LL
Complete the following reactions. Br 2) g) NaOMe NaCN H2, Pd/C CI
1. Predict the products of the following reactions. excess NaNH2 THE Br Br H 1. NaNH2 2. CH3CH,Br H2SO4, H20 Hz, Pd/BaSO4 quinoline, CH3OH Na, NH3 1 equivalent HBO NaNH2 Br (excess) 1. Sia,BH, THE 2. H2O2, NaOH HgSO4 H2SO4 H2O
6. Identify the most likely mechanism and identify the products aromatic substitution reactions. of the following nueleophilic Ci 1) NaOH, 350°C 2) HCl, H20 1) NaNH2 1) NaOH, 350 °C 2) HCI, H20 ︿Br Cl O2N 6. Identify the most likely mechanism and identify the products aromatic substitution reactions. of the following nueleophilic Ci 1) NaOH, 350°C 2) HCl, H20 1) NaNH2 1) NaOH, 350 °C 2) HCI, H20 ︿Br Cl O2N
Predict the products of the following reactions. Na, NH3 1 equivalent HBr f. Br NaNH2 (excess) Br g. 1. Sia BH, THF 2. H202, NaOH h. HgSO HSO HO I
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
Chapter 18 Part II (Nucleophilic Aromatic Substitution) Please record answers using the corresponding Blackboard assessment link located in the Graded Assignment Folders on Blackboard. 1. What is/are the major product (s) of the following reaction? Choose all that apply NaOCH2CH NO2 ? F NO2 F NO2 NO2 NO2 В C A 2. Which of the following compounds will react with NaOH the fastest? NaOH fastest reaction? NO2 NO2 Cl. Cl CI 02N NO2 NO2 В A 3. What is/are the...
1. What substitution mechanism will the following reaction likely proceed through? (1pt) CH3 HU. : N=C: +3C-Br - NC-C WH + Br HT 2. Label the componetns of the above reation as: Nucleophile, electrophile, leaving group (3pt) 3. Assign R and S configuration to the following reactant and products (2pt) NaOH HO + HO-COCH3 H.COwc-OH + HO-6 H2COCCI H H 4. What ratio should the two above products be formed in and what is their stereochemical relationship? (2pt) 5. Predict...
Predict the major product for the following reactions (a) Cl2 AICI (b) H2SO4 ОН (c) COOH CH3CH2I AICI3 (d) NaCN Br (e) O2N. ,NO2 NaSCH3 (f) ОН (g) Cl. 1. KMnO4/NaOH 2. HC
20. Predict the major product in the following reactions: ︿Br 1) NaCN 2) MeMgBr CN 1)EtMgBr 2) H,o 3) LAH 4) H20 CN heat 21