Question

2) Put the sun Von the most be conforto 3) Assign Ror S configuration for the following compounds: COOH "снусна HANH H OH NO ! CH₂ 3CH3 3 CH₂ COOH 4) Assign the following pairs as enantiomers, diastereomers or meso: CH, CH OH OH Br Br- Br- HB- HH- H -Br Br HH Br IHH MICH, сіну Hн Cats

it would be great if you could explain your answers so that I can understand better

Answer 1

2) Structure I is most stable because both CH3 group are at maximum distance thus repulsion between them is minimum, hence it is most stable.

3) In R/S configuration, atoms or groups are numbered according to their atomic mass if atom attached to chiral carbon is same then next atom is considered for priority determination. If rotation from high priority group (1) to low priority group (3) is clockwise with group numbered as 4 lie Below the plane (or horizontal) then it is R and if anticlockwise then S.

If low priority group lie above the plane (vertically) then clockwise rotation give S and anticlockwise rotation give R.

4) Enantiomers are non-superimposable mirror images.

Diastereomers are stereoisomers with same bond connectivity but they are not mirror images.

Meso compound contain internal plane which cleave the molecule into two equal halves.

A) Enantiomers because they are mirror images.

B) Diastereomers because they are stereoisomers but not mirror images.

C) Meso compound because they contain internal plane of symmetry.

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