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A person has a pituitary tumor with increased secretion of ADH. They might develop secondary hypertension due to increased: 1
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Answer #1

Antidiuretic hormone (ADH), also known as vasopressin, is a small peptide hormone which regulates the body’s retention of water.

ADH acts in the kidney to regulate the volume and osmolarity of the urine. Specifically, it acts in the distal convoluted tubule (DCT) and collecting ducts (CT) cells.

The increase in ADH release will mean that the permeability of the DCT and CT cells to water increases and urine output decreases. This happens because ADH increases the transcription and insertion of Aquaporin–2 channels to the apical membrane of the DCT and CT cells. This allows water to move down its concentration gradient, out of the nephron and back into the blood stream. This increases the water reabsorbed from the urine, in order to decrease plasma osmolality and increase total blood volume. Water reabsorption in this manner is a passive process.

thus option A is correct answer. Water reabsorption is the cause of secondary hypertension.

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