Question

Is fentanyl soluble or insoluble in water and explain why or why not.

Is fentanyl soluble or insoluble in water and explain why or why not.

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Answer #1

Answer:

fentanyl is soluble in water.

Explanation:

Structure of the Fentanyl :

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The presence of an amide group act as a source for intermolecular hydrogen bonding with water.

Again the piperidine group enhances the solubility in water. The nitrogen of the N-methyl-piperidine group has a lone pair and can also form a hydrogen bond with water. This acts as a hydrogen bond acceptor.

Hence the molecule fentanyl is soluble in water.

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