A. First hydrolysis of acetal gives aldehyde then intramolecular Aldol condensation gives enone then conjugate addition of CN-.
B. Aldol condensation gives enone then Nucleophilic addition of Grignard reagent gives tertiary alcohol.
4. Provide the products of each reaction (3pts, 2pts) 1. H,O* OCH; 2. NaOCH, CHOH OCH,...
4. Provide the products of each reaction (3pts, 2pts) 1. H2O+ OCH; 2. NaOCH, CHOH OCH 3. H, A 4. NaCN 1. LDA 2. Pho 3. H , A 4. EtMgBr 5. Provide an arrow-pushing mechanism for the reaction below, and state how many product stereoisomers are possible (5 pts) NO2 cat. KOH ЕКОН
4. Provide the products of each reaction (3pts, 2pts) 1. HO- Осн. 2. NaOCH CH,OH ? OCH 3. H.A 4. NaCN 1. LDA 2. Pho 3. H, A 4. EtMgBr
4. Provide the products of each reaction (3pts. 2pts) 1. H30 OCH3 2. NaOCH; CHOH2 OCH 3. Ht, A 4. NaCN 1. LDA 2 Pho 3. H+, A 4 EtMg Br
Provide the products of each reaction (3pts, 2pts) 1. HgO* 2. NaOCH3 4. OCH HORD OCH3 3. Η ' Δ 4. NaCN 1. LDA 2. Ph 3. H, A 4. EtMgBr
O P enter return U K shift ? Aldal Codesafra Readn 4. Provide the products of each reaction (3pts, 2pts) 1. H30* 2. NaOCH3 CH OH 3. H*, A 4. NaCN OCH3 OCH3 ? 1. LDA 2. Ph ? 3. H*, A 4. EtMgBr
NaOH сн. then heat NaOH yer then heat NaOH (CH3),Culi then heat 1. NaOCH Снзон OCH 2. dil. HCI 1. LDA 1. LIATHA 2. Br 2.H30* 1. NaOCH lich, 2.phor 1. NaOCH, OCH, 2. Ph Br 2. CI 3. H30+, heat 1. LDA 1. LDA o 2. 0 CI 3. H3O+ H 3. H3O+
predict the products of the following reactions 0 () CH,CH CCH,-C-OCH, NocCH (2) CH (3) Ho .heat (I) NaOCH2CH (2) H,O', heat (b) CH,-C-CH-C-OCH,CH,+ CH, (1) LDA -OH (c) Ph CH, () CH,CH,CH,Br (1) H2C-CH CH,Br (2) H0* OCH, NaOCH Ph (2) CH,CH,CH2CH2Br (g) product from part (f) (decarboxylation) 0 () CH,CH CCH,-C-OCH, NocCH (2) CH (3) Ho .heat (I) NaOCH2CH (2) H,O', heat (b) CH,-C-CH-C-OCH,CH,+ CH, (1) LDA -OH (c) Ph CH, () CH,CH,CH,Br (1) H2C-CH CH,Br (2) H0*...
What is the major product obtained from the following reaction: OCH Br NaOCH OCH CH OH BI OCH, 0 1 2 3 What is the major organic product obtained from the following reaction (KOtBu = OC(CH3)31 big bulky base)? 0-Bu 2 KOBU BUCH 0.tBu W08 0-Bu 1 2 3 0 4
1. NaOCH; 2. CH3CH2Br 3. H2O* heat Love OCH3 ОСН3 o OCH3 Which reaction sequence would accomplish this transformation? Joego LDA H30* heat H H2Cr2O7 monog morangayan H30*/CH3CH2OH NaOCH2CH3/heat LDA (CH3)2CHMOBrNaOH, heat NaOH heat [(CH3)2CH]>Culi
4. (31 pts) Provide the reaction products and indicate the type of reactions ( I, UL, TE EZ) and optical activity (Yes or No) in the round rectangles, respectively. If reaction does not take place, indicate "No Reaction" in the box Draw 2 major products Reaction type Snd Draw 1 minor product Reaction type EL VW Is the product optically active? ha Draw 1 product Reaction type EZ Сн,он NaCN acetone Is the product optically active? ho Br Draw 1...