Question

Question 1 1. The pediatrician of one of your patients calls your pharmacy and asks you to compound a prescription for one of his patients. He would like Drug X in a syrup form at a concentration of 50 mg/teaspoonful. He prescribes 120 mL and says the patient should take 1 teaspoonful every 12 hours. He then says, "You can figure out the rest." You do some research about Drug X and find the following information: 1. It has a bitter taste 2. It is has a solubility of 1g/100 mL in water and 1g/5mL in alcohol. You look in the patient's profile and find the following: 3. He is 6 /2 years old. 4. He has no known drug allergies or pre-existing medical conditions (you have verified this with the doctor's office and the patient's mother). 5. In the past he has asked for berry flavored medicine. Given all .of this information, please suggest a recipe and directions for compounding for this prescription

Answer 1

As mentioned in the question drug concentration should be 50 mg/ 5 ml and a total of 120 ml is prescribed. It is also mentioned that this drug has a bitter taste. Additionally, patient is 6.5 year old and demanded berry flavoured syrups in the past. Therefore, water solution containing artificial flavour can be used to mask the bitterness of the drug as this drug has solubility of 1g/100 ml. If we convert it in mg then it is 10 mg/ml.

Patient is advised to have 50 mg/5 ml so it is matching when we make a water solution.