1. What is a Coombs Check cell and what do Coombs Check cells control for? 2.Provide...
1. What is a Coombs Check cell and what do Coombs Check cells control for?
2.Provide two examples of times in the blood bank laboratory you might want to complete Rh phenotyping?
3. Explain the phenomenon of dosage by creating two different sets of Rh phenotype results and discussing how cells with those phenotypes could be used to show dosage.
Homework Answers
Coombs check or control cells are nothis but antibody coated RBCs with IgG antibody. Freshly isolated RBCs are incubated with IgG and then washed followed by preservation with antibiotics. Shelf like is approximately 4 weeks.
Coombs cells are used to detect autoimmune induced hemolytic anemia. in tis case antibodies are against its own body RBCs. if the coombs test is positive indicates autoimmune disease.
Also coombs test is done before transfusion.
It is of 2 types direct & indirect test. Application includes mycoplasmic infection, infevtion mononucleosis, chronic leukaemic leukemia etc
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1. What is a Coombs Check cell and what do Coombs Check cells
control for?
2.Provide...
answer question #2 a-f e.) What is the prognosis for those effected? Check Your Understanding 1....
answer question #2 a-f
e.) What is the prognosis for those effected? Check Your Understanding 1. When someone is admitted to the hospital, one of the first procedures that health professionals perform is a blood draw. One lab value that is checked is a white blood cell (WBC) count. If the WBC count is high (normal range - 4,000 -11,000/mma, this could indicate the presence of an infection. Further analysis (called a differential) is performed to determine the relative prevalence...
2 The inheritance of autosomal dominant traits also can be explored through pedigree analysis, Polydactylism, having...
2 The inheritance of autosomal dominant traits also can be explored through pedigree analysis, Polydactylism, having extra digits, results from a dominant gene (P). Using Figure 3.8, explain the appearance of polydactyly in children of generation 3. O IIION FUR 8.8 Polydactylism pedigree. X-linked traits are carried exclusively on the X chromosome. Because a male possesses only one X chromosome, if he receives an X chromosome that carries an X-linked trat he will express that trait. For a female to...
Human blood types A, B and O are associated with the carbohydrate antigens A, B and...
Human blood types A, B and O are associated with the carbohydrate antigens A, B and H respectively. A and B antigens are caused by an alteration of H antigen. Normally everyone can synthesize H antigen (a cell surface carbohydrate found on red blood cells and other cell types). Some people make A and/or B transferase(s) which converts the H antigen to an A and/or B antigen respectively. The H antigen is produced by a specific fucosyltransferase encoded by the...
Check Your Understanding 3.1 1 What are chromosomes made of? number 2 How many chromosomes are...
Check Your Understanding 3.1 1 What are chromosomes made of? number 2 How many chromosomes are in a human somatic cell? 46 chromosomes 3 The term used to refer to this full complement of chromosomes is the 4 How many chromosomes are in human gametes? 5 This is referred to as the number 6 Wa chicken's skin cell has 78 chromosomes, how many chromosomes would the chicken's sperm cell have? 7 How can we distinguish the 23 types of chromosomes...
1. What are the different sources of energy available to living organisms? 2. How do the...
1. What are the different sources of energy available to living organisms? 2. How do the acquisition and the use of energy by living organisms work according to the laws of thermodynamics? 3. Explain the energy use in the following reactions: endergonic/exergonic. 4. What is metabolism? How are chemical reactions related to metabolism? Why is energy needed to run a metabolism? What are coupled reactions? 5. Draw a picture of ATP. Why is this molecule so important for cells? How...
immunology practing samples and not sure if my answers correct. 1. NK cells are effective against...
immunology
practing samples and not sure if my answers correct.
1. NK cells are effective against viral infections because many virus infected cells a. are susceptible to lysis b. are susceptible to phagocytosis c. show reduced levels of MHC class I molecules d. show reduced levels of MHC class II molecules e. none of the above 2. Arachidonic acid serves as a substrate in the lipoxygenase and cyclooxygenase pathways resulting in the production of a. histamine, leukotrienes b. leukotrienes, prostaglandins...
QUESTION 1 Although SARS-CoV-2 is currently a global health threat, how might we turn it into...
QUESTION 1 Although SARS-CoV-2 is currently a global health threat, how might we turn it into a tool for biotechnology? a. It could possibly be turned into a viral vector against lung cancers b. Its promoters might be used to express genes in lung cells c. Its surface proteins could be used for new epitope tags d. All of the above QUESTION 2 Which of the following are applications of molecular assembly described in this course? a. It can be...
Chapter 2: Quality Assurance and Legal issues in Case Studies Case Study 2-1: Quality Assurance in...
Chapter 2: Quality Assurance and Legal issues in Case Studies Case Study 2-1: Quality Assurance in a Cow Laboratory Cow Laboratory in a large internal medicine group QUESTIONS actice performed over 50 waived tests a day. The medical assistants and the phlebotomists who performed 1. What are CLIA and CLIACI he waved testing were all trained it was obvious 2. Why is CLA visiting their site from the inconsistent results recorded on the cumulative eart that everyone's technique differed somewhat...
Question: The whole process before administering blood can be broken down into the following nine activities:...
Question: The whole process before administering blood can be broken down into the following nine activities: A. Register B. Consult and take tests C. Sample blood D. Deliver blood sample to lab E. Deliver blood to bank (CBS) F. Deliver test blood to lab (CBS) G. Cross-match H. Retrieve blood from bank I. Deliver blood to the clinic (Note: Administering blood is a pure medical activity. This activity will be excluded since your the analysis will not help to reduce...
1. Fill out the following table by indicating which general technique (light microscopy (LM) or electron...
1. Fill out the following table by indicating which general technique (light microscopy (LM) or electron microscopy (EM]) could be used to observe each structure or phenomenon. Put "no" in the box if the technique could not be used. If light microscopy can be used, name one technique (bright-field, phase-contrast, fluorescence, etc.) that you think would be effective. You will find some useful information in Appendix 1 of this manual and Chapter 18 of your textbook. Structure or phenomenon Could...
answer question #2 a-f
e.) What is the prognosis for those effected? Check Your Understanding 1. When someone is admitted to the hospital, one of the first procedures that health professionals perform is a blood draw. One lab value that is checked is a white blood cell (WBC) count. If the WBC count is high (normal range - 4,000 -11,000/mma, this could indicate the presence of an infection. Further analysis (called a differential) is performed to determine the relative prevalence...
2 The inheritance of autosomal dominant traits also can be explored through pedigree analysis, Polydactylism, having extra digits, results from a dominant gene (P). Using Figure 3.8, explain the appearance of polydactyly in children of generation 3. O IIION FUR 8.8 Polydactylism pedigree. X-linked traits are carried exclusively on the X chromosome. Because a male possesses only one X chromosome, if he receives an X chromosome that carries an X-linked trat he will express that trait. For a female to...
Human blood types A, B and O are associated with the carbohydrate antigens A, B and H respectively. A and B antigens are caused by an alteration of H antigen. Normally everyone can synthesize H antigen (a cell surface carbohydrate found on red blood cells and other cell types). Some people make A and/or B transferase(s) which converts the H antigen to an A and/or B antigen respectively. The H antigen is produced by a specific fucosyltransferase encoded by the...
Check Your Understanding 3.1 1 What are chromosomes made of? number 2 How many chromosomes are in a human somatic cell? 46 chromosomes 3 The term used to refer to this full complement of chromosomes is the 4 How many chromosomes are in human gametes? 5 This is referred to as the number 6 Wa chicken's skin cell has 78 chromosomes, how many chromosomes would the chicken's sperm cell have? 7 How can we distinguish the 23 types of chromosomes...
1. What are the different sources of energy available to living organisms? 2. How do the acquisition and the use of energy by living organisms work according to the laws of thermodynamics? 3. Explain the energy use in the following reactions: endergonic/exergonic. 4. What is metabolism? How are chemical reactions related to metabolism? Why is energy needed to run a metabolism? What are coupled reactions? 5. Draw a picture of ATP. Why is this molecule so important for cells? How...
immunology
practing samples and not sure if my answers correct.
1. NK cells are effective against viral infections because many virus infected cells a. are susceptible to lysis b. are susceptible to phagocytosis c. show reduced levels of MHC class I molecules d. show reduced levels of MHC class II molecules e. none of the above 2. Arachidonic acid serves as a substrate in the lipoxygenase and cyclooxygenase pathways resulting in the production of a. histamine, leukotrienes b. leukotrienes, prostaglandins...
Chapter 2: Quality Assurance and Legal issues in Case Studies Case Study 2-1: Quality Assurance in a Cow Laboratory Cow Laboratory in a large internal medicine group QUESTIONS actice performed over 50 waived tests a day. The medical assistants and the phlebotomists who performed 1. What are CLIA and CLIACI he waved testing were all trained it was obvious 2. Why is CLA visiting their site from the inconsistent results recorded on the cumulative eart that everyone's technique differed somewhat...
1. Fill out the following table by indicating which general technique (light microscopy (LM) or electron microscopy (EM]) could be used to observe each structure or phenomenon. Put "no" in the box if the technique could not be used. If light microscopy can be used, name one technique (bright-field, phase-contrast, fluorescence, etc.) that you think would be effective. You will find some useful information in Appendix 1 of this manual and Chapter 18 of your textbook. Structure or phenomenon Could...
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