Question

11 and 12 please let me know if its either True or False.

11) Raising the pH from 8 to 10 reduces the catalytic efficiency (keat/ Km) of chymotrypsin by increasing Км. 12) Assuming that the association between the PDGF receptor and Src is mediated by an inter-molecula interaction between the SH2 domain of Src and a phosphorylated tyrosine on the PDGF receptor, the Km for this inter-molecular association would likely be much lower than the Km for the intra- molecular association of this SH2 domain with phosphorylated Tyr 527.

Answer 1

- 1) Raising the pH from 8 to 10 reduces efficiency (Keat / km) of chymotrypsin by increaring km - Thue 2) Assunidhia thap kue arou'arbu beleveen the PDGF seceptor and sie lis medialed by an inter-molcular interaction deween the sta domani of Src. and a phosphorylated tryp tyrosine on the PD GIF receptor. then km for this auter-molecular association would much likely be much lower than km for the intra-molecular anociation of SH₂ domain with phosphorlyated Tyr 527 & true