Question

Please answer sections a thru d:

12. Lysozyme unfolds at 351 K. The enthal py of unfolding is 552 kJ/mol at 351 K The difference in heat capacity that results from unfolding is +6.3 kJ K mol. The difference in heat capacity is independent of temperature a) What is the entropy change upon heating lysozyme from 25 °C to 78 °C? b) What is the entropy change of denaturing lysozyme at 351K? c) What is the entropy change upon cooling denatured/u nfo l ded lysozyme from 351 K to 298 K? d) What is the ent ropy of unfold ing of lysozyme at 298K?

Answer 1

12. enfolds at 351K 78'c AH351K 552 KTIm ATCP 6.3 KT/K moL 35 AS= AH 25 C-8'c a 298 6.3 xl3 n 351 JKmor 298 AS=1031. 26JEmo 35KAH351K 552xloTmor 35IK 11 351K T S351K1572.65 Jkmot c) 351K 298K Coaoling 298K fust severse b) is palding T 351k AS -l031 26 JK mol d) (351-248 - 6.3M0 AH AH351K K K 298K JImol k 6-3tlo 53) 552 3 Jmort BH248K JMot

AH298K218100 s/mol 2181 oD TIMo AH2a8K AS 298K K 298 T 731.88 T mot