Question

6 ame: 5. Give the products of the following aromatic substitution reactions (20 pts): HIO4 а. NaOMe Br heat HNO3 HO H2SO 0F0 Cl2(PCY32RU CHCeHs) CH2Cl2, 25°C CH2l2 e. Zn(Cu) diethyl ether enton

Answer 1

a) alkene reacts with HIO4 forms the diols and then undergoes the oxidative cleavage and forms the carbonyl compounds

b) NaOMe is strong base and forms the both substitution and elimination products with secondary alkyl halides

c) -OH is strong ortho para directing group so it directs the -NO2 group at ortho position to the -OH group

d) thereaction grubbs reaction

e) alkene reacts with CH2I2 Zn Cu it undergoes the cyclo propanation reaction and it is called as Simmons Smith reaction

NH HTOY HO HOTY... et pour et sociale Nome Heat omo SN product at HNO3 O1 Here artne chake 932 Ru=CHIGHS CHicks 2500 Grubbs catalyst (Reseton) es em CHLIZ. znes diettyl ether Cyclopropanceton Sevmoon's smith Recetion