Question

I need help on all of these please

1. Draw the energy diagram that correctly depicts the following reaction (AG<0) and the transition state for the rate determining step. Label substrate (S), product (P), and intermediate (1) if applicable. OTS + NaBr TsONa polar aprotic solvent transition state free energy reaction progress 2. Complete the following reaction schemes. CH3OH 0°C alkyl halide nucleophile ТА polar aprotic solvent 3. Compound A and B are constitutional isomers with molecular formula C5H11Br. When treated with DBU both compounds give the same monosubstituted alkene product. Draw structures of A and B.

Answer 1

Brun C OTS Transition state Energy Na activation energy Reactant TAH - product + TSONG AGRO Reachon progress-> Transition State: 8- OTS * си он produch CEY syt си reaction product polar apronic solvent

O ATB are constitutional isomer with molecular formula: C5H11 Br 4 both gives some monosubstituted product of alkene Mono substituted alkene formed by above compound E This is a product Now we use a DBU (1,8-Diazablcyclo [5.4.0] undec-7-ene) There are two probable reactant Role of DBU is as a base & reaction takes place via E² mechanism. o DBU T-bromo pentare Mono substituted alkene Mono substituted product DBU is bulky base so it proton from less hindered we ger mono- substytuted can abstract side & therefore olkene produch-