5. Show how you could synthesize the following. (16 pts) A Using the Wittig reaction y...
Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation. НО не он PhPh.
Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation. No mechanisms are required for this question. You do not need to show formation of the Grignard reagent. [2 marks] HO H3COH Ph Phi
predict the product. explain how would you get the correct answers to the 3 questions. We were unable to transcribe this imageWe were unable to transcribe this image2. Synthesize the following compound using the Wittig reaction (6 points) 3 Carbons - 4 carbone 3. Synthesize the following compound using the correct aldehyde or ketone and t Grignard reagent. (6 points) OH OH Hovho Con 10 2. Show how you can synthesize the following alkene from cyclopentanol. (Hint 3 Stop) Him...
1) Predict the major product in each of the following transformations. Show the mechanism. 2) Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation. Include the mechanism. Predict the major product in each of the following transformations. No mechanisms are required for this question. [3 Marks] 1. CH,сн,МgBr (еxcess) 2. HС{aq) 1. PhMgBr (1 equiv.) 2. HCI(aq) ОН HO 1. CH2MgBr (2 equiv.) 2. HCl(aq) Н Show how...
Use retrosynthetic analysis to suggest two paths to synthesize 2-methyl-3-pentanol using the Grignard reaction. (Click and drag the appropriate image to the correct position in the following reactions.) Aldehyde Grignard route 1 MgBr OH H,O or Aldehyde Grignard 2-methyl-3-pentanol route 2 CH3CH2CH MgBr 0 CH,CHMgBr CHy CH CH,Mg8
VII. (8 pts) How could you use the Diels-Alder reaction to synthesize the compound whose structure is given below. Propose a mechanism. H.CO. CO2CH3 H,C01
3. Show how you would add a Grignard reagent to an acid chloride to synthesize 4-phenylheptan-4-01 4. Show how you would accomplish the following synthesis in good yield. OH benzoic acid N.N-dimethylbenzamide NH HO hexanol heptane-1-amine 0 0 methyl 2-phenylacetate 3-phenylpropionitrile но-л-он
Jame: . Complete this mechanism for the following substitution reaction. Note: this reaction is balanced. H-Br Н,0 OH -CH3 H20 Step 1: proton transfer Step 2: lose water Step 3: attack the carbocation Br -CH3 . Each reaction above is reversible. In question 1, what effect would adding more HBr have on the equilibrium? Would there be more or less alkyl bromide product present at equilibrium? . Two dehydrations can occur on glycerol, the principle carrier molecule in vaping devices....
Could you help me formulate multiple ways to synthesize the following product? Each appears to be applying the Grignard reaction, however, ultimately a different reagent must be used in order to recieve credit. Any tips, answers, or suggestions? The first photo below is the target molecule! We were unable to transcribe this imagethe missing reagent for the following reactions. You WILL NOT get any credit if you use Q3. Draw the missing reagent for the follow same reagents again and...
13. What is the major organic product of the following reaction? ma POCI OH 16-POCIE CIZOPO 14. Which of the following statements about Grignard reagents (R-Mg-X) is true? (i) because of the highly polar nature of the Mg-X and Mg-C bonds in Grignard reagents, water and CH3OH are good solvents for Grignard reactions. (ii) reaction of a Grignard reagent with an aldehyde yields a secondary alcohol; (iii) Grignard reagents are strongly nucleophilic; (a) only () is true (d) only (i)...