Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation.
1) When an grignard reagent reacts with a formaldehyde an primary alcohol is formed . Since the benzyl alcohol is a primary alcohol thus it can be formed by the reaction of a formaldehyde ( electrophilic center ) and a grignard reagent.
The detail reaction mechanism is shown below.
1) When an ester compound reacts with a grignard reagent a tertiary alcohol is generated.
Since the compound is a tertiary alcohol, it can be formed by the ethyl acetate ( electrophilic center) and the corresponding grignard reagent.
The detail reaction mechanism is shown below.
Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by...
Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation. No mechanisms are required for this question. You do not need to show formation of the Grignard reagent. [2 marks] HO H3COH Ph Phi
1) Predict the major product in each of the following transformations. Show the mechanism. 2) Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation. Include the mechanism. Predict the major product in each of the following transformations. No mechanisms are required for this question. [3 Marks] 1. CH,сн,МgBr (еxcess) 2. HС{aq) 1. PhMgBr (1 equiv.) 2. HCI(aq) ОН HO 1. CH2MgBr (2 equiv.) 2. HCl(aq) Н Show how...
Predict the major product in each of the following transformations. No mechanisms are required for this question. [3 Marks] 1. CH3CH2MgBr (excess) 2. HCl(aq) 1. PhMgBr (1 equiv.) 2. HCl(aq) ОН о но 1. CH3MgBr (2 equiv.) 2. HCl(aq) н Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced equation. No mechanisms are required for this question. You do not need to show formation of the Grignard reagent. [2...
Show how you would synthesize the following acid using carbonation of a Grignard reagent. Show how you would synthesize the following acid using carbonation of a Grignard reagent.
Q2) Complete the missing reagents Q3) propose one way to synthesize the products using Grignard reagent PLS HELP!! thank you Q3) Propose one way to synthesize the products using Grignard reagent. a) d) g) ОН ОН ОН b) e) h) ОН ОН ОН ОН f) ОН Q2) complete the missing reagents a) ОН ОН olan OCH3 b) ОН -Br d) ОН -Br CO2H е) 9) -СІ ОН ОН
3. Show how you would add a Grignard reagent to an acid chloride to synthesize 4-phenylheptan-4-01 4. Show how you would accomplish the following synthesis in good yield. OH benzoic acid N.N-dimethylbenzamide NH HO hexanol heptane-1-amine 0 0 methyl 2-phenylacetate 3-phenylpropionitrile но-л-он
Propose one way to synthesize the products using Grignard reagent. a) d) 9) ОН он ОН ОН b) ОН е) h) ОН с) ОН ОН f) ОН
5. Show how you could synthesize the following. (16 pts) A Using the Wittig reaction y vang Ho wang reason Mo + Phypoger 8 ОН Hint: Use the appropriate aldehyde or ketone, and a Grignard Reagent 6. Write the mechanism for the following reaction. (8 points) OH 1. emger 2. H₂O*
Predict the major product in each of the following transformations. No mechanisms are required for this question. Predict the major product in each of the following transformations. No mechanisms are required for this question. [3 Marks] 1. CH,CHMgBr (excess) hoy 2. HCl(aq) i 1. PhMgør (1 equiv.) 1. PhMgBr (1 equiv.) 2. HCl(aq) охон 1. CH3MgBr (2 equiv.) 2. HCl(aq) Show how you could synthesize the products below using a Grignard reagent and appropriate electrophile by drawing the overall balanced...
skip 5b 4. Show how you would synthesize the following aldehydes by adding the appropriate Grignard reagent to formaldehyde. (a) H (b) H 5. Predict the products of the following reactions: (a) 1.) LIAIH 2.) H,0 (b) CH,CH2CH2CH,CENH CH,CH,M B , then H,0* + 1.) DIBAL-H (-78 C) (c) 2.) H,O OCH3 1) DIBAL-H (-78 C) 2.) H,O 3